479347-86-9 | 6 -硝基- 7 - 硫氨基苯并[F]喹喔啉-2,3二酮
英文名称
6-Nitro-7-sulfamoylbenzo[f]quinoxaline-2,3-dione, Disodium Salt
分子式
C24H14N8Na2O12S2
分子量
716.52
结构式
英文别名
| 属性 | 值 |
|---|---|
| 形态 | 结晶固体 |
| 颜色 | 橙色 |
| 溶解度 | Soluble in H2O |
| 稳定性 | 储存在-20°C的冰箱中 |
| 储存条件 | -20°C冷冻 |
| 水溶解性 | 溶于水至100mM |
| 标题 | 内容 |
|---|---|
| 靶点 | AMPA receptor |
| 体内研究 | NBQX disodium (FG9202; 20 mg/kg, i.p.; for 3 days) decreases seizures induced by PTZ. NBQX disodium is neuroprotective in a focal ischaemia model in the rat when given as an i.v. bolus dose of 30 mg/kg at the time of MCA occlusion and again at 1 h post occlusion. Animal Model: Male Wistar rats that weighed 220-240 g with pentylenetetrazole (PTZ) Dosage: 20 mg/kg Administration: IP; for 3 days Result: Effectively reversed the behavioral abnormality of epileptic seizures of chronic PTZ administration (50mg/kg; i.p.; for 28 days) in rats. |
| 体外研究 | NBQX disodium (FG9202 disodium) has a high affinity for AMPA and kainate binding sites with little or no affinity for the glutamate recognition site on the NMDA receptor complex. |
| 生物活性 | NBQX disodium (FG9202 disodium) 是高度选择性，竞争型的 AMPA 受体拮抗剂。NBQX disodium 具有神经保护和抗惊厥活性。 |
479347-86-9
相关产品
| 商城编码 | 产品名称 | 标准值 | 规格 | CAS号 | 库存 | 标准价 | 品牌 | 数量 | 操作 |
|---|---|---|---|---|---|---|---|---|---|
| ZTR-N550005 | 6-Nitro-7-sulfamoylbenzo[f]quinoxaline-2,3-dione, Disodium Salt|ZTR-N550005|10mg|CAS:479347-86-9 |
见证书
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10mg
|
479347-86-9
|
0
|
咨询
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萘析精选
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| ZC-21715 | NBQX sodium salt|ZC-21715|≥98%|10 mg|CAS:479347-86-9 |
≥98%
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10 mg
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479347-86-9
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0
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2150.0
|
萘析精选
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