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BRCA1 (phospho Ser1423) antibody介绍:

产品名称:
BRCA1 (phospho Ser1423) antibody
别名:
BRCA1 DNA repair associated , BRCAI , BRCC1 , BROVCA1 , FANCS , IRIS , PNCA4 , PPP1R53 , PSCP , RNF53
反应种属:
Human, Mouse, Rat
宿主来源:
Rabbit
实验应用:
ICC/IF, IHC-P, WB
同种型:
IgG
免疫原:
A synthetic phosphorylated peptide around S1423 of human BRCA1 (NP_009225.1).
克隆性:
Polyclonal
克隆号:
纯化方式:
Purified by affinity chromatography
偶联:
Unconjugated
产品浓度:
Batch dependent (Please refer to the vial label for the specific concentration.)
保存温度:
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
运输温度:
4°C
预期分子量:
208
产品形式:
Liquid
存储溶液:
PBS, 50% Glycerol, 0.02% sodium azide.
生产商:
GeneTex
功能与背景:
This gene encodes a nuclear phosphoprotein that plays a role in maintaining genomic stability, and it also acts as a tumor suppressor. The encoded protein combines with other tumor suppressors, DNA damage sensors, and signal transducers to form a large multi-subunit protein complex known as the BRCA1-associated genome surveillance complex (BASC). This gene product associates with RNA polymerase II, and through the C-terminal domain, also interacts with histone deacetylase complexes. This protein thus plays a role in transcription, DNA repair of double-stranded breaks, and recombination. Mutations in this gene are responsible for approximately 40% of inherited breast cancers and more than 80% of inherited breast and ovarian cancers. Alternative splicing plays a role in modulating the subcellular localization and physiological function of this gene. Many alternatively spliced transcript variants, some of which are disease-associated mutations, have been described for this gene, but the full-length natures of only some of these variants has been described. A related pseudogene, which is also located on chromosome 17, has been identified. [provided by RefSeq, May 2009]

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BRCA1 (phospho Ser1423) antibody|GTX03784|100μl 国标解读

BRCA1 (phospho Ser1423) antibody|GTX03784|100μl 为本库在售产品。经核查,本库标准库中未收录其专属产品质量国家标准,对其质量与安全性评价可依据化学试剂通用试验方法标准与安全类标准执行

标准号标准名称适用说明
GB/T 619-1988化学试剂 采样及验收规则试剂取样与验收通用程序
GB/T 6682-2008分析实验室用水规格和试验方法试验用水要求
GB/T 9724-2007化学试剂 pH值测定通则酸碱度表征
GB/T 9735-2008化学试剂 重金属测定通用方法重金属杂质控制
GB/T 9736-2008化学试剂 酸度和碱度测定通用方法酸度/碱度
GB/T 9738-2008化学试剂 水不溶物测定通用方法水不溶物
GB/T 9739-2006化学试剂 铁测定通用方法铁杂质
GB/T 9741-2008化学试剂 灼烧残渣测定通用方法灼烧残渣
GB/T 9737-2008化学试剂 易炭化物质测定通则易炭化物质
GB 15346-2012化学试剂 包装及标志包装与标识
GB 13690-2009化学品分类和危险性公示 通则危险性分类
GB/T 16483-2008化学品安全技术说明书 内容和项目顺序安全信息(SDS)
GB 15258-2009化学品安全标签编写规定安全标签
GB 30000.18-2013化学品分类和标签规范 第18部分:急性毒性急性毒性标签

说明:本库内暂无该产品的专属产品质量国家标准,以上为化学试剂通用试验方法标准与安全类标准,实际验收应以生产企业标准或合同约定为准

以上标准解读仅供参考,请以相应标准的原文为准!

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