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PF-429242 (hydrochloride)
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PF-429242 (hydrochloride)

15140-1 mg
PF-429242 (hydrochloride)
¥ 737.0
¥ 737.0
2248666-66-0
1 mg
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PF-429242 (hydrochloride)介绍：

产品名称:
PF-429242 (hydrochloride)
产品描述:
A site-1 protease inhibitor (IC50 =170 nM against human recombinant site-1 protease); selective for site-1 protease over trypsin, elastase, proteinase K, plasmin, kallikren, factor XIa, thrombin, and furin at concentrations up to 100 μM; inhibits proteolytic processing and nuclear translocation of SREBP; reduces expression of HMG-CoA synthase and fatty acid synthase (EC50s = 0.3 and 2 μM, respectively) and inhibits cholesterol synthesis (EC50 = 600 nM) in HepG2 cells; reduces cholesterol and fatty acid synthesis in CD-1 mice; inhibits replication of dengue virus serotypes 1-4 in infected HeLa cells; reduces growth of T98G, U87-MG, and A172 glioblastoma cells (IC50s = 0.32, 15.2, and 27.6 μM, respectively)
保存温度:
-20
运输温度:
-20
预期分子量:
409.58
产品形式:
A crystalline solid
有效期:
1460
纯度:
≥95%
CAS号:
2248666-66-0
分子式:
C25H35N3O2 • 2HCl

本公司销售的所有产品仅供实验科研使用，不用于人体及临床诊断。

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