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DCTN1 antibody [C3], C-term|GTX100231-S|25μl
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DCTN1 antibody [C3], C-term|GTX100231-S|25μl

GTX100231-S
DCTN1 antibody [C3], C-term
¥ 1700.0
¥ 1700.0
25μl
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DCTN1 antibody [C3], C-term介绍:

产品名称:
DCTN1 antibody [C3], C-term
别名:
dynactin subunit 1 , DAP-150 , DP-150 , P135
反应种属:
Human, Mouse, Rat
宿主来源:
Rabbit
实验应用:
ICC/IF, IHC-P, WB
同种型:
IgG
免疫原:
Carrier-protein conjugated synthetic peptide encompassing a sequence within the C-terminus region of human DCTN1. The exact sequence is proprietary.
克隆性:
Polyclonal
克隆号:
纯化方式:
Purified by antigen-affinity chromatography.
偶联:
Unconjugated
产品浓度:
1 mg/ml (Please refer to the vial label for the specific concentration.)
保存温度:
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
运输温度:
4°C
预期分子量:
142
产品形式:
Liquid
存储溶液:
0.1M Tris, 0.1M Glycine, 20% Glycerol, 0.01% Thimerosal.
生产商:
GeneTex
功能与背景:
This gene encodes the largest subunit of dynactin, a macromolecular complex consisting of 10 subunits ranging in size from 22 to 150 kD. Dynactin binds to both microtubules and cytoplasmic dynein. Dynactin is involved in a diverse array of cellular functions, including ER-to-Golgi transport, the centripetal movement of lysosomes and endosomes, spindle formation, chromosome movement, nuclear positioning, and axonogenesis. This subunit interacts with dynein intermediate chain by its domains directly binding to dynein and binds to microtubules via a highly conserved glycine-rich cytoskeleton-associated protein (CAP-Gly) domain in its N-terminus. Alternative splicing of this gene results in multiple transcript variants encoding distinct isoforms. Mutations in this gene cause distal hereditary motor neuronopathy type VIIB (HMN7B) which is also known as distal spinal and bulbar muscular atrophy (dSBMA). [provided by RefSeq]

本公司销售的所有产品仅供实验科研使用,不用于人体及临床诊断。

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