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PML antibody|GTX05122|100μl
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PML antibody|GTX05122|100μl

GTX05122
PML antibody
¥ 6600.0
¥ 6600.0
100μl
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PML antibody介绍：

产品名称:
PML antibody
别名:
MYL,PML,PP8675,RNF71,TRIM19,promyelocytic leukemia
反应种属:
Human
宿主来源:
Rabbit
实验应用:
IHC-P, WB
靶标/特异性:
This antibody is specific for isoform 1, 9, 10 and 11 of PML protein.
同种型:
IgG
免疫原:
Synthetic peptide directed towards the C terminal region of human PML: EGPSTLRVLDENLADPQAEDRPLVFFDLKIDNETQKISQLAAVNRESKFR
克隆性:
Polyclonal
克隆号:
纯化方式:
Purified by affinity chromatography
偶联:
Unconjugated
产品浓度:
0.5 mg/ml (Please refer to the vial label for the specific concentration.)
保存温度:
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
运输温度:
4°C
预期分子量:
98
产品形式:
Liquid
存储溶液:
PBS, 2% Sucrose, 0.09% Sodium azide.
生产商:
GeneTex
功能与背景:
The protein encoded by this gene is a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. This phosphoprotein localizes to nuclear bodies where it functions as a transcription factor and tumor suppressor. Its expression is cell-cycle related and it regulates the p53 response to oncogenic signals. The gene is often involved in the translocation with the retinoic acid receptor alpha gene associated with acute promyelocytic leukemia (APL). Extensive alternative splicing of this gene results in several variations of the protein's central and C-terminal regions; all variants encode the same N-terminus. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2008]

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