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TERT antibody|GTX05257|400μl
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TERT antibody|GTX05257|400μl

GTX05257
TERT antibody
¥ 5900.0
¥ 5900.0
400μl
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TERT antibody介绍:

产品名称:
TERT antibody
别名:
CMM9,DKCA2,DKCB4,EST2,PFBMFT1,TCS1,TERT,TP2,TRT,hEST2,hTRT,telomerase reverse transcriptase,hTERT,Telomerase reverse transcriptase
反应种属:
Human
宿主来源:
Rabbit
实验应用:
FCM, ICC/IF, WB
同种型:
IgG
免疫原:
A synthetic peptide between 627-656 amino acids from the Central region of human TERT.
克隆性:
Polyclonal
克隆号:
纯化方式:
Purified by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS
偶联:
Unconjugated
产品浓度:
Batch dependent (Please refer to the vial label for the specific concentration.)
保存温度:
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
运输温度:
4°C
预期分子量:
127
产品形式:
Liquid
存储溶液:
PBS, 0.09% Sodium azide.
生产商:
GeneTex
功能与背景:
Telomerase is a ribonucleoprotein polymerase that maintains telomere ends by addition of the telomere repeat TTAGGG. The enzyme consists of a protein component with reverse transcriptase activity, encoded by this gene, and an RNA component which serves as a template for the telomere repeat. Telomerase expression plays a role in cellular senescence, as it is normally repressed in postnatal somatic cells resulting in progressive shortening of telomeres. Deregulation of telomerase expression in somatic cells may be involved in oncogenesis. Studies in mouse suggest that telomerase also participates in chromosomal repair, since de novo synthesis of telomere repeats may occur at double-stranded breaks. Alternatively spliced variants encoding different isoforms of telomerase reverse transcriptase have been identified; the full-length sequence of some variants has not been determined. Alternative splicing at this locus is thought to be one mechanism of regulation of telomerase activity. [provided by RefSeq, Jul 2008]

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