白假丝酵母定量菌株

Quantitative strains of candida albicans

《消毒技术规范》中医疗器械灭菌效果检测用菌,《GB 4789.15-2016 食品安全国家标准 食品微生物学检验 霉菌和酵母计数》阳性对照菌株，2015版中国药典质控菌株。公共用品用具微生物,GB/T 18204.5-2013 公共场所卫生检验方法 第5部分：集中空调通风系统,GB 4789.15-2016 食品安全国家标准 食品微生物学检验 霉菌和酵母计数,GB 4789.28-2013 食品安全国家标准 食品微生物学检验 培养基和试剂的质量要求；《化妆品技术规范》霉菌和酵母菌检验方法 阳性对照菌株。

菌落直径为1-2mm，圆形，边缘整齐，不透明，正面乳白色，中间凸起，表面光滑，质地湿润，易挑起，不产色素，G＋（蓝紫色），球菌，纯度：纯

酵母浸粉：3.0g，麦芽提取物：3.0g，葡萄糖：10.0g，酪蛋白胨：5.0g，琼脂：20.0g，pH：6.2±0.2（25℃）

30℃；24-48h；好氧；

菌液培养18h左右，吸取1ml加入80ml保护剂中混匀，1瓶分装0.4ml

-20℃

西林瓶

‖Intended Use │‖Antigenic Properties│Serotype A RefWagner T, et al. pH-dependent denaturation of extracellular aspartic proteinases from Candida species. J. Med. Vet. Mycol. 33 275-278, 1995. PubMed 8531028‖Viability│post-FreezeViability test‖Sequenced Data│18S ribosomal RNA gene, partial sequence; internal transcribed spacer 1, 5.8S ribosomal RNA gene, and internal transcribed spacer 2, complete sequence; and 26S ribosomal RNA gene, partial sequence GGTTTCCGTAGGTGAACCTGCGGAAGGATCATTACTGATTTGCTTAATTGCACCACATGTGTTTTTCTTTGAAACAAACTTGCTTTGGCGGTGGGCCCAGCCTGCCGCCAGAGGTCTAAACTTACAACCAATTTTTTATCAACTTGTCACACCAGATTATTACTAATAGTCAAAACTTTCAACAACGGATCTCTTGGTTCTCGCATCGATGAAGAACGCAGCGAAATGCGATACGTAATATGAATTGCAGATATTCGTGAATCATCGAATCTTTGAACGCACATTGCGCCCTCTGGTATTCCGGAGGGCATGCCTGTTTGAGCGTCGTTTCTCCCTCAAACCGCTGGGTTTGGTGTTGAGCAATACGACTTGGGTTTGCTTGAAAGACGGTAGTGGTAAGGCGGGATCGCTTTGACAATGGCTTAGGTCTAACCAAAAACATTGCTTGCGGCGGTAACGTCCACCACGTATATCTTCAAACTTTGACCTCAAATCAGGTAGGACTACCCGCTGAACTTAAGCATATCAATAA D1D2 region of the 26S ribosomal RNA gene ATATCAATAAGCGGAGGAAAAGAAACCAACAGGGATTGCCTCAGTAGCGGCGAGTGAAGCGGCAAAAGCTCAAATTTGAAATCTGGCGTCTTTGGCGTCCGAGTTGTAATTTGAAGAAGGTATCTTTGGGCCCGGCTCTTGTCTATGTTCCTTGGAACAGGACGTCACAGAGGGTGAGAATCCCGTGCGATGAGATGACCCGGGTCTGTGTAAAGTTCCTTCGACGAGTCGAGTTGTTTGGGAATGCAGCTCTAAGTGGGTGGTAAATTCCATCTAAAGCTAAATATTGGCGAGAGACCGATAGCGAACAAGTACAGTGATGGAAAGATGAAAAGAACTTTGAAAAGAGAGTGAAAAAGTACGTGAAATTGTTGAAAGGGAAGGGCTTGAGATCAGACTTGGTATTTTGCATGCTGCTCTCTCGGGGGCGGCCGCTGCGGTTTACCGGGCCAGCATCGGTTTGGAGCGGCAGGATAATGGCGGAGGAATGTGGCACGGCTTCTGCTGTGTGTTATAGCCTCTGACGATACTGCCAGCCTAGACCGAGGACTGCGGTTTTTAACCTAGGATGTTGGCATAATGATCTTAA‖Cross References│Nucleotide (GenBank) D86430 Candida albicans gene for CaRho1, complete cds.
Nucleotide (GenBank) AX109674 Sequence 407 from Patent WO0123604.
Nucleotide (GenBank) X56867 C. albicans gene for secretory aspartate proteinase.
Nucleotide (GenBank) AF031229 Candida albicans alternative oxidase (AOX1) gene, complete cds.
Nucleotide (GenBank) U38534 Candida albicans alpha-tubulin (TUB1) gene, complete cds.
Nucleotide (GenBank) L22737 Candida albicans inositol-1-phosphate synthase (IN01) gene, complete cds.
Nucleotide (GenBank) AF031228 Candida albicans D-arabinono-1,4-lactone oxidase (ALO) gene,
Nucleotide (GenBank) U40454 Candida albicans topoisomerase type I (CATOP1) gene, complete cds.
Nucleotide (GenBank) EU266569 ITS including 5.8S rRNA gene‖描述│Assay of amphotericin B fungizone
Assay of antimicrobial preservatives
Assay of haloprogin
Assay of nystatin fungicidin
Media testing
Membrane filter testing
Preparatory test control
Produces D-arabinolactone oxidase
Produces DNA topoisomerase
Food testing
Pharmaceutical and Personal Care
Produces aspartic proteinases aspartyl proteinases
Produces estrogen-binding protein
Produces lanosterol synthase 2,3-oxidosqualene lanosterol cyclase
Produces phenethyl alcohol
Produces polyamine oxidase
Produces tryptophol
Quality control strain
Sterility testing
Testing
Testing fungicides
Produces farnesoic acid, an autoregulatory substance capable of regulating morphological transition
Reference strain for performance testing culture media listed by the ISO TC 34 SC 9 Joint Working Group 5 in the ISO 11133 and by the Working Party on Culture Media of the International Committee on Food Microbiology and Hygiene (ICFMH-WPCM)
This strain is recommended by ATCC for use in the tests described in ASTM Standard Test Method E979-91 where only the taxon is specified.;This strain is recommended by ATCC for use in the tests described in ASTM Standard Test Method E979-91 where only the taxon is specified.
For sterility testing, not more than five passages from the ATCC culture should be used.
Growth and invasiveness in mouse
Steroid interference with antifungal activity
Cell wall hydrophobicity enhances corticosterone incorporation.
Ultraviolet microscopy
Calcification
Morphology and physiology of strain sectors
Use of impedance for preservative efficacy testing
Fungitoxicity of alcohols and fatty acids
Esterase activity
Lipid composition
Effect of antineoplastic drugs