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NLRP3 (Internal) blocking peptide|GTX89303-PEP|100μg
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NLRP3 (Internal) blocking peptide|GTX89303-PEP|100μg

GTX89303-PEP
NLRP3 (Internal) blocking peptide
¥ 3200.0
¥ 3200.0
100μg
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NLRP3 (Internal) blocking peptide介绍：

产品名称:
NLRP3 (Internal) blocking peptide
别名:
Nlr Family Pyrin Domain Containing 3 , Agtavprl , Aii , Avp , C1Orf7 , Cias1 , Clr1.1 , Dfna34 , Fcas , Fcas1 , Fcu , Kefh , Mws , Nalp3 , Pypaf1 , Nlrp3
靶标/特异性:
The peptide was used in the production of GTX89303.
克隆号:
产品浓度:
保存温度:
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
运输温度:
4°C
产品形式:
Lyophilized powder
存储溶液:
Reconstitute with 200μl distilled water to obtain a 0.5mg/ml peptide solution. Lyophilized from 5% (v/v) acetonitrile/H₂O, no preservatives.
生产商:
GeneTex
功能与背景:
This gene encodes a pyrin-like protein containing a pyrin domain, a nucleotide-binding site (NBS) domain, and a leucine-rich repeat (LRR) motif. This protein interacts with the apoptosis-associated speck-like protein PYCARD/ASC, which contains a caspase recruitment domain, and is a member of the NALP3 inflammasome complex. This complex functions as an upstream activator of NF-kappaB signaling, and it plays a role in the regulation of inflammation, the immune response, and apoptosis. Mutations in this gene are associated with familial cold autoinflammatory syndrome (FCAS), Muckle-Wells syndrome (MWS), chronic infantile neurological cutaneous and articular (CINCA) syndrome, and neonatal-onset multisystem inflammatory disease (NOMID). Multiple alternatively spliced transcript variants encoding distinct isoforms have been identified for this gene. Alternative 5' UTR structures are suggested by available data; however, insufficient evidence is available to determine if all of the represente

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