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SHP2 (phospho Tyr542) antibody介绍:

产品名称:
SHP2 (phospho Tyr542) antibody
别名:
protein tyrosine phosphatase non-receptor type 11 , BPTP3 , CFC , JMML , METCDS , NS1 , PTP-1D , PTP2C , SH-PTP2 , SH-PTP3 , SHP2
反应种属:
Human, Mouse
宿主来源:
Rabbit
实验应用:
IHC-P, WB
同种型:
IgG
免疫原:
The antiserum was produced against a chemically synthesized phosphopeptide derived from the region of human SHP2 that contains tyrosine 542. The sequence is conserved in mouse, rat and chicken.
克隆性:
Polyclonal
克隆号:
纯化方式:
Purified by antigen-affinity chromatography
偶联:
Unconjugated
产品浓度:
Batch dependent (Please refer to the vial label for the specific concentration.)
保存温度:
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
运输温度:
4°C
预期分子量:
68
产品形式:
Liquid
存储溶液:
PBS, 0.1% BSA, 50% Glycerol, 0.05% Sodium azide.
生产商:
GeneTex
功能与背景:
The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP contains two tandem Src homology-2 domains, which function as phospho-tyrosine binding domains and mediate the interaction of this PTP with its substrates. This PTP is widely expressed in most tissues and plays a regulatory role in various cell signaling events that are important for a diversity of cell functions, such as mitogenic activation, metabolic control, transcription regulation, and cell migration. Mutations in this gene are a cause of Noonan syndrome as well as acute myeloid leukemia. [provided by RefSeq, Aug 2016]

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