Name: SETD7 antibody [N1C1]
Brand: 萘析精选
SKU: GTX117333
Price: 4000.00 CNY
Availability: OutOfStock

图片仅供参考，具体产品以实物为准！

SETD7 antibody [N1C1]|GTX117333|100μl

产品编号

GTX117333

英文名称

SETD7 antibody [N1C1]

标准价

~~¥ 4000.0~~

优惠价

¥ 4000.0

CAS号

规格

100μl

有效期

品牌

萘析精选

标准值

见详情

数量

− +

库存

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特性值	规格	库存	货期	有效期	标准价	数量	操作
见详情	25μl	0			1700.0

SETD7 antibody [N1C1]介绍：

产品名称:

SETD7 antibody [N1C1]

别名:

SET domain containing 7, histone lysine methyltransferase , KMT7 , SET7 , SET7/9 , SET9

反应种属:

Human

宿主来源:

Rabbit

实验应用:

同种型:

IgG

免疫原:

Recombinant protein encompassing a sequence within the center region of human SETD7. The exact sequence is proprietary.

克隆性:

Polyclonal

克隆号:

纯化方式:

Purified by antigen-affinity chromatography.

偶联:

Unconjugated

产品浓度:

1 mg/ml (Please refer to the vial label for the specific concentration.)

保存温度:

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

运输温度:

4°C

预期分子量:

产品形式:

Liquid

存储溶液:

PBS, 1% BSA, 20% Glycerol, 0.01% Thimerosal.

生产商:

GeneTex

功能与背景:

Histone methyltransferase that specifically monomethylates 'Lys-4' of histone H3. H3 'Lys-4' methylation represents a specific tag for epigenetic transcriptional activation. Plays a central role in the transcriptional activation of genes such as collagenase or insulin. Recruited by IPF1/PDX-1 to the insulin promoter, leading to activate transcription. Has also methyltransferase activity toward non-histone proteins such as p53/TP53, TAF10, and possibly TAF7 by recognizing and binding the [KR]-[STA]-K in substrate proteins. Monomethylates 'Lys-189' of TAF10, leading to increase the affinity of TAF10 for RNA polymerase II. Monomethylates 'Lys-372' of p53/TP53, stabilizing p53/TP53 and increasing p53/TP53-mediated transcriptional activation. Also able to demethylated 'Lys-372' of p53/TP53 in vitro.

本公司销售的所有产品仅供实验科研使用，不用于人体及临床诊断。

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