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Her2 / ErbB2 (phospho Tyr1221/Tyr1222) antibody|GTX133445|100μl
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Her2 / ErbB2 (phospho Tyr1221/Tyr1222) antibody|GTX133445|100μl

GTX133445
Her2 / ErbB2 (phospho Tyr1221/Tyr1222) antibody
¥ 4000.0
¥ 4000.0
100μl
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25μl
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Her2 / ErbB2 (phospho Tyr1221/Tyr1222) antibody介绍：

产品名称:
Her2 / ErbB2 (phospho Tyr1221/Tyr1222) antibody
别名:
erb-b2 receptor tyrosine kinase 2 , CD340 , HER-2 , HER-2/neu , HER2 , MLN 19 , NEU , NGL , TKR1
反应种属:
Human
宿主来源:
Rabbit
实验应用:
IHC-P, WB
同种型:
IgG
免疫原:
Carrier-protein conjugated synthetic peptide surrounding phospho Tyr1221/Tyr1222 of human Her2 / ErbB2. The exact sequence is proprietary.
克隆性:
Polyclonal
克隆号:
纯化方式:
Purified by antigen-affinity chromatography.
偶联:
Unconjugated
产品浓度:
0.88 mg/ml (Please refer to the vial label for the specific concentration.)
保存温度:
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
运输温度:
4°C
预期分子量:
138
产品形式:
Liquid
存储溶液:
PBS, 1% BSA, 20% Glycerol, 0.025% ProClin 300.
生产商:
GeneTex
功能与背景:
This gene encodes a member of the epidermal growth factor (EGF) receptor family of receptor tyrosine kinases. This protein has no ligand binding domain of its own and therefore cannot bind growth factors. However, it does bind tightly to other ligand-bound EGF receptor family members to form a heterodimer, stabilizing ligand binding and enhancing kinase-mediated activation of downstream signalling pathways, such as those involving mitogen-activated protein kinase and phosphatidylinositol-3 kinase. Allelic variations at amino acid positions 654 and 655 of isoform a (positions 624 and 625 of isoform b) have been reported, with the most common allele, Ile654/Ile655, shown here. Amplification and/or overexpression of this gene has been reported in numerous cancers, including breast and ovarian tumors. Alternative splicing results in several additional transcript variants, some encoding different isoforms and others that have not been fully characterized. [provided by RefSeq]

本公司销售的所有产品仅供实验科研使用，不用于人体及临床诊断。

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