Name: DUT antibody
Brand: 萘析精选
SKU: GTX117563-S
Price: 1700.00 CNY
Availability: OutOfStock

图片仅供参考，具体产品以实物为准！

DUT antibody|GTX117563-S|25μl

产品编号

GTX117563-S

英文名称

DUT antibody

标准价

~~¥ 1700.0~~

优惠价

¥ 1700.0

CAS号

规格

25μl

有效期

品牌

萘析精选

标准值

见详情

数量

− +

库存

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DUT antibody介绍：

产品名称:

DUT antibody

别名:

deoxyuridine triphosphatase , dUTPase

反应种属:

Human

宿主来源:

Rabbit

实验应用:

IHC-P, IP, WB

同种型:

IgG

免疫原:

Recombinant protein encompassing a sequence within the center region of human DUT. The exact sequence is proprietary.

克隆性:

Polyclonal

克隆号:

纯化方式:

Purified by antigen-affinity chromatography.

偶联:

Unconjugated

产品浓度:

0.49 mg/ml (Please refer to the vial label for the specific concentration.)

保存温度:

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

运输温度:

4°C

预期分子量:

产品形式:

Liquid

存储溶液:

0.1M Tris, 0.1M Glycine, 20% Glycerol, 0.01% Thimerosal.

生产商:

GeneTex

功能与背景:

This gene encodes an essential enzyme of nucleotide metabolism. The encoded protein forms a ubiquitous, homotetrameric enzyme that hydrolyzes dUTP to dUMP and pyrophosphate. This reaction serves two cellular purposes: providing a precursor (dUMP) for the synthesis of thymine nucleotides needed for DNA replication, and limiting intracellular pools of dUTP. Elevated levels of dUTP lead to increased incorporation of uracil into DNA, which induces extensive excision repair mediated by uracil glycosylase. This repair process, resulting in the removal and reincorporation of dUTP, is self-defeating and leads to DNA fragmentation and cell death. Alternative splicing of this gene leads to different isoforms that localize to either the mitochondrion or nucleus. A related pseudogene is located on chromosome 19. [provided by RefSeq]

本公司销售的所有产品仅供实验科研使用，不用于人体及临床诊断。

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