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MATN3 antibody|GTX85286|100μg
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MATN3 antibody|GTX85286|100μg

GTX85286
MATN3 antibody
¥ 6200.0
¥ 6200.0
100μg
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MATN3 antibody介绍:

产品名称:
MATN3 antibody
别名:
matrilin 3 , DIPOA , EDM5 , HOA , OADIP , OS2
反应种属:
Human, Mouse, Rat
宿主来源:
Rabbit
实验应用:
ELISA, ICC/IF, WB
靶标/特异性:
This antibody is specific for MATN3 Internal
同种型:
IgG
免疫原:
MATN3 antibody was raised against a 13 amino acid synthetic peptide from near the center of human MATN3.The immunogen is located within amino acids 180 - 230 of MATN3.
克隆性:
Polyclonal
克隆号:
纯化方式:
Purified by antigen-affinity chromatography
偶联:
Unconjugated
产品浓度:
1 mg/ml (Please refer to the vial label for the specific concentration.)
保存温度:
Store as concentrated solution. Centrifuge briefly prior to opening vial. Store at 4ºC.
运输温度:
4°C
预期分子量:
53
产品形式:
Liquid
存储溶液:
PBS, 0.02% Sodium azide.
生产商:
GeneTex
功能与背景:
Matrilins (MATNs) are a family of non-collagenous extra-cellular matrix (ECM) proteins consisting of four known members that have been proposed to play key roles in modulating cellular phenotypes during chondrogenesis of mesenchymal stem cells (MSCs). MATN1 and MATN3 are expressed specifically in cartilage and are among the most up-regulated ECM proteins during chondrogenesis. MATN3 is composed of a single N-terminal von Willebrand Factor A (vWFA) domain followed by four epidermal growth factor (EGF) repeats and a coiled-coil domain whereas MATN1 is composed of two vWFA domains separated by one EGF-like domain. MATN1 or MATN3 may play a role in modulating chondrogenesis during the chondrocyte differentiation process. Mutations of this gene have been associated with variety of inherited chondrodysplasias. Recent studies show that aberrant expression and processing of MATN3 are hallmarks of conventional cartilaginous neoplasms.

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