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PD-L2 antibody|GTX85449|100μg
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PD-L2 antibody|GTX85449|100μg

GTX85449
PD-L2 antibody
¥ 6200.0
¥ 6200.0
100μg
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PD-L2 antibody介绍:

产品名称:
PD-L2 antibody
别名:
programmed cell death 1 ligand 2 , B7DC , Btdc , CD273 , PD-L2 , PDCD1L2 , PDL2 , bA574F11.2
反应种属:
Human, Mouse, Rat
宿主来源:
Rabbit
实验应用:
ELISA, IHC-P, WB
同种型:
IgG
免疫原:
PD-L2 antibody was raised against a 16 amino acid synthetic peptide from near the center of human PD-L2.The immunogen is located within amino acids 140 - 190 of PD-L2.
克隆性:
Polyclonal
克隆号:
纯化方式:
Purified by antigen-affinity chromatography
偶联:
Unconjugated
产品浓度:
1 mg/ml (Please refer to the vial label for the specific concentration.)
保存温度:
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
运输温度:
4°C
预期分子量:
31
产品形式:
Liquid
存储溶液:
PBS, 0.02% Sodium azide.
生产商:
GeneTex
功能与背景:
Cell-mediated immune responses are initiated by T lymphocytes that are themselves stimulated by co gnate peptides bound to MHC molecules on antigen-presenting cells (APC). T-cell activation is generally self-limited as activated T cells express receptors such as PD-1 (also known as PDCD-1) that mediate inhibitory signals from the APC. PD-1 can bind two different but related ligands, PDL-1 and PDL-2, both of which are thought act as a negative regulator of T cell activation. However, it has been suggested that PDL-2 can act to stimulate an immunogenic response through and alternative receptor from PD-1. At least three isoforms of PDL-2 are known to exist; this antibody is specific to the largest isoform. PDL-2 antibody has no cross-reactivity to PDL-2.

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