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SART1 blocking peptide|GTX89682-PEP|100μg
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SART1 blocking peptide|GTX89682-PEP|100μg

GTX89682-PEP
SART1 blocking peptide
¥ 3200.0
¥ 3200.0
100μg
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SART1 blocking peptide介绍：

产品名称:
SART1 blocking peptide
别名:
Spliceosome Associated Factor 1, Recruiter Of U4/U6.U5 Tri-Snrnp , Ara1 , Haf , Homs1 , Sart1259 , Snrnp110 , Snu66 , Sart1
靶标/特异性:
The peptide was used in the production of GTX89682.
克隆号:
产品浓度:
保存温度:
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
运输温度:
4°C
产品形式:
Lyophilized powder
存储溶液:
Reconstitute with 200μl distilled water to obtain a 0.5mg/ml peptide solution. Lyophilized from 5% (v/v) acetonitrile/H₂O, no preservatives.
生产商:
GeneTex
功能与背景:
This gene encodes two proteins, the SART1(800) protein expressed in the nucleus of the majority of proliferating cells, and the SART1(259) protein expressed in the cytosol of epithelial cancers. The SART1(259) protein is translated by the mechanism of -1 frameshifting during posttranscriptional regulation; its full-length sequence is not published yet. The two encoded proteins are thought to be involved in the regulation of proliferation. Both proteins have tumor-rejection antigens. The SART1(259) protein possesses tumor epitopes capable of inducing HLA-A2402-restricted cytotoxic T lymphocytes in cancer patients. This SART1(259) antigen may be useful in specific immunotherapy for cancer patients and may serve as a paradigmatic tool for the diagnosis and treatment of patients with atopy. The SART1(259) protein is found to be essential for the recruitment of the tri-snRNP to the pre-spliceosome in the spliceosome assembly pathway. [provided by RefSeq, Jul 2008]

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