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FGFR2 antibody, Internal|GTX88618|100μg
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FGFR2 antibody, Internal|GTX88618|100μg

GTX88618
FGFR2 antibody, Internal
¥ 5600.0
¥ 5600.0
100μg
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FGFR2 antibody, Internal介绍：

产品名称:
FGFR2 antibody, Internal
别名:
fibroblast growth factor receptor 2 , BBDS , BEK , BFR-1 , CD332 , CEK3 , CFD1 , ECT1 , JWS , K-SAM , KGFR , TK14 , TK25
反应种属:
Human
宿主来源:
Goat
实验应用:
WB
靶标/特异性:
This antibody is expected to recognise all reported isoforms except isoform 7 (NP_001138389.1). The immunizing peptide represents part of the extracellular domain.
同种型:
IgG
免疫原:
Peptide with sequence C-GREKEITASPDY, from the internal region of the protein sequence according to NP_000132.3; NP_075259.4; NP_001138385.1; NP_001138386.1; NP_001138387.1; NP_001138388.1; NP_001138390.1; NP_001138391.1.
克隆性:
Polyclonal
克隆号:
纯化方式:
Purified by ammonium sulphate precipitation followed by antigen affinity chromatography
偶联:
Unconjugated
产品浓度:
0.50 mg/ml (Please refer to the vial label for the specific concentration.)
保存温度:
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
运输温度:
4°C
预期分子量:
92
产品形式:
Liquid
存储溶液:
TBS, 0.5% BSA, 0.02% Sodium azide.
生产商:
GeneTex
功能与背景:
The protein encoded by this gene is a member of the fibroblast growth factor receptor family, where amino acid sequence is highly conserved between members and throughout evolution. FGFR family members differ from one another in their ligand affinities and tissue distribution. A full-length representative protein consists of an extracellular region, composed of three immunoglobulin-like domains, a single hydrophobic membrane-spanning segment and a cytoplasmic tyrosine kinase domain. The extracellular portion of the protein interacts with fibroblast growth factors, setting in motion a cascade of downstream signals, ultimately influencing mitogenesis and differentiation. This particular family member is a high-affinity receptor for acidic, basic and/or keratinocyte growth factor, depending on the isoform. Mutations in this gene are associated with Crouzon syndrome, Pfeiffer syndrome, Craniosynostosis, Apert syndrome, Jackson-Weiss syndrome, Beare-Stevenson cutis gyrata syndrome, Saethre-Chotzen syndrome, and syndromic craniosynostosis. Multiple alternatively spliced transcript variants encoding different isoforms have been noted for this gene. [provided by RefSeq, Jan 2009]

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