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BLNK antibody, C-term|GTX89949|100μg
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BLNK antibody, C-term|GTX89949|100μg

GTX89949
BLNK antibody, C-term
¥ 5600.0
¥ 5600.0
100μg
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BLNK antibody, C-term介绍:

产品名称:
BLNK antibody, C-term
别名:
B cell linker , AGM4 , BASH , BLNK-S , LY57 , SLP-65 , SLP65 , bca
反应种属:
Human
宿主来源:
Goat
实验应用:
WB
靶标/特异性:
This antibody is expected to recognize both reported isoforms (NP_037446.1; NP_001107566.1).
同种型:
IgG
免疫原:
Peptide with sequence C-KDSTRLKYAVKVS, from the C Terminus of the protein sequence according to NP_037446.1; NP_001107566.1.
克隆性:
Polyclonal
克隆号:
纯化方式:
Purified by ammonium sulphate precipitation followed by antigen affinity chromatography
偶联:
Unconjugated
产品浓度:
0.50 mg/ml (Please refer to the vial label for the specific concentration.)
保存温度:
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
运输温度:
4°C
预期分子量:
50
产品形式:
Liquid
存储溶液:
TBS, 0.5% BSA, 0.02% Sodium azide.
生产商:
GeneTex
功能与背景:
This gene encodes a cytoplasmic linker or adaptor protein that plays a critical role in B cell development. This protein bridges B cell receptor-associated kinase activation with downstream signaling pathways, thereby affecting various biological functions. The phosphorylation of five tyrosine residues is necessary for this protein to nucleate distinct signaling effectors following B cell receptor activation. Mutations in this gene cause hypoglobulinemia and absent B cells, a disease in which the pro- to pre-B-cell transition is developmentally blocked. Deficiency in this protein has also been shown in some cases of pre-B acute lymphoblastic leukemia. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, May 2012]

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