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Mib antibody介绍:

产品名称:
Mib antibody
别名:
mindbomb E3 ubiquitin protein ligase 1 , cg5841 , chunp6889 , fe47f05 , im:7148100 , mib , wu:fe47f05
反应种属:
Zebrafish
宿主来源:
Rabbit
实验应用:
IHC-Wm
同种型:
IgG
免疫原:
Recombinant protein encompassing a sequence within the N-terminus region of zebrafish Mib. The exact sequence is proprietary.
克隆性:
Polyclonal
克隆号:
纯化方式:
Purified by antigen-affinity chromatography.
偶联:
Unconjugated
产品浓度:
1 mg/ml (Please refer to the vial label for the specific concentration.)
保存温度:
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
运输温度:
4°C
产品形式:
Liquid
存储溶液:
PBS, 20% Glycerol, 0.01% Thimerosal.
生产商:
GeneTex
功能与背景:
E3 ubiquitin-protein ligase that mediates ubiquitination of Delta receptors, which act as ligands of Notch proteins. Positively regulates the Delta-mediated Notch signaling by ubiquitinating the intracellular domain of Delta, leading to endocytosis of Delta receptors. It thereby participates in many processes regulated by the Notch signaling pathway, such as midline cell fate specification prior to germ layer formation, patterning of sensory cell differentiation in the ear, neurogenesis of the hindbrain and commitment to a secretory fate in the intestine. Essential for early embryonic development.

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