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KCNN3 antibody介绍:

产品名称:
KCNN3 antibody
别名:
potassium calcium-activated channel subfamily N member 3 , KCa2.3 , SK3 , SKCA3 , hSK3
反应种属:
Human, Mouse, Rat
宿主来源:
Rabbit
实验应用:
WB
同种型:
IgG
免疫原:
Peptide (C)KQIGSLESKLEHLTAS, corresponding to amino acid residues 659-674 (Intracellular, C-terminal part) of human KCNN3 (Accession : Q9UGI6).
克隆性:
Polyclonal
克隆号:
纯化方式:
Purified by antigen-affinity chromatography
偶联:
Unconjugated
产品浓度:
0.8 mg/ml (Please refer to the vial label for the specific concentration.)
保存温度:
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
运输温度:
4°C
预期分子量:
81
产品形式:
Liquid
存储溶液:
PBS, 1% BSA, 0.05% Sodium azide.
生产商:
GeneTex
功能与背景:
Action potentials in vertebrate neurons are followed by an afterhyperpolarization (AHP) that may persist for several seconds and may have profound consequences for the firing pattern of the neuron. Each component of the AHP is kinetically distinct and is mediated by different calcium-activated potassium channels. This gene belongs to the KCNN family of potassium channels. It encodes an integral membrane protein that forms a voltage-independent calcium-activated channel, which is thought to regulate neuronal excitability by contributing to the slow component of synaptic AHP. This gene contains two CAG repeat regions in the coding sequence. It was thought that expansion of one or both of these repeats could lead to an increased susceptibility to schizophrenia or bipolar disorder, but studies indicate that this is probably not the case. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Feb 2011]

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