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Her2 / ErbB2 antibody [ERB2/776]|GTX34781|100μg
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Her2 / ErbB2 antibody [ERB2/776]|GTX34781|100μg

GTX34781
Her2 / ErbB2 antibody [ERB2/776]
¥ 7000.0
¥ 7000.0
100μg
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Her2 / ErbB2 antibody [ERB2/776]介绍：

产品名称:
Her2 / ErbB2 antibody [ERB2/776]
别名:
CD340 , ERBB2 , HER2 , HER2/neu , MLN 19 , NEU , NGL , TKR1 , erbb2 receptor tyrosine kinase 2 , Her2 , ErbB2 , Neu , EGFR2 , erb-b2 receptor tyrosine kinase 2
反应种属:
Human
宿主来源:
Mouse
实验应用:
ELISA, FCM, ICC/IF
靶标/特异性:
This MAb is specific to c-erbB-2/HER-2 and shows minimal cross-reaction with other members of the family.
同种型:
IgG1
免疫原:
Recombinant intracellular domain of human HER-2 protein
克隆性:
Monoclonal
克隆号:
ERB2/776
纯化方式:
Protein A/G purified
偶联:
Unconjugated
产品浓度:
0.2 mg/ml (Please refer to the vial label for the specific concentration.)
保存温度:
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
运输温度:
4°C
产品形式:
Liquid
存储溶液:
PBS, 0.05% BSA, 0.05% Sodium azide.
生产商:
GeneTex
功能与背景:
This gene encodes a member of the epidermal growth factor (EGF) receptor family of receptor tyrosine kinases. This protein has no ligand binding domain of its own and therefore cannot bind growth factors. However, it does bind tightly to other ligand-bound EGF receptor family members to form a heterodimer, stabilizing ligand binding and enhancing kinase-mediated activation of downstream signalling pathways, such as those involving mitogen-activated protein kinase and phosphatidylinositol-3 kinase. Allelic variations at amino acid positions 654 and 655 of isoform a (positions 624 and 625 of isoform b) have been reported, with the most common allele, Ile654/Ile655, shown here. Amplification and/or overexpression of this gene has been reported in numerous cancers, including breast and ovarian tumors. Alternative splicing results in several additional transcript variants, some encoding different isoforms and others that have not been fully characterized. [provided by RefSeq, Jul 2008]

本公司销售的所有产品仅供实验科研使用，不用于人体及临床诊断。

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