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OLR1 / LOX-1 antibody [23C11]|GTX54456|50μg
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OLR1 / LOX-1 antibody [23C11]|GTX54456|50μg

GTX54456
OLR1 / LOX-1 antibody [23C11]
¥ 5300.0
¥ 5300.0
50μg
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OLR1 / LOX-1 antibody [23C11]介绍：

产品名称:
OLR1 / LOX-1 antibody [23C11]
别名:
CLEC8A,LOX1,LOXIN,OLR1,SCARE1,SLOX1,oxidized low density lipoprotein receptor 1,LOX-1
反应种属:
Human, Mouse
宿主来源:
Mouse
实验应用:
FCM, ICC/IF, IHC-P, Neutralizing /Inhibition
靶标/特异性:
The monoclonal antibody 23C11 recognizes oxidized low-density lipoprotein receptor-1 (LOX-1). Monoclonal antibody 23C11 neutralizes LOX-1 and inhibits Hsp70 binding to dendritic cells and Hsp70-induced antigen cross-presentation. In vivo, targeting LOX-1 with a tumor antigen using anti-LOX-1 antibody 23C11 induces anti-tumor immunity.
同种型:
IgG1
免疫原:
Fusion protein of extracellular domain (aa 71-273) of human LOX-1 with murine Fcγ1 (LOX-1-muFc) produced in PEAK cells
克隆性:
Monoclonal
克隆号:
23C11
纯化方式:
Purified IgG1
偶联:
Unconjugated
产品浓度:
100 μg/ml (Please refer to the vial label for the specific concentration.)
保存温度:
Store as concentrated solution. Centrifuge briefly prior to opening vial. Store at 4ºC.
运输温度:
4°C
产品形式:
Liquid
存储溶液:
Filter-sterilized PBS, 0.1% BSA, no preservatives.
生产商:
GeneTex
功能与背景:
This gene encodes a low density lipoprotein receptor that belongs to the C-type lectin superfamily. This gene is regulated through the cyclic AMP signaling pathway. The encoded protein binds, internalizes and degrades oxidized low-density lipoprotein. This protein may be involved in the regulation of Fas-induced apoptosis. This protein may play a role as a scavenger receptor. Mutations of this gene have been associated with atherosclerosis, risk of myocardial infarction, and may modify the risk of Alzheimer's disease. Alternate splicing results in multiple transcript variants.[provided by RefSeq, Feb 2010]

本公司销售的所有产品仅供实验科研使用，不用于人体及临床诊断。

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