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Chk1 (phospho Ser345) antibody [HL122]|GTX635572|100μl
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Chk1 (phospho Ser345) antibody [HL122]|GTX635572|100μl

GTX635572
Chk1 (phospho Ser345) antibody [HL122]
¥ 4000.0
¥ 4000.0
100μl
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Chk1 (phospho Ser345) antibody [HL122]介绍:

产品名称:
Chk1 (phospho Ser345) antibody [HL122]
别名:
checkpoint kinase 1 , CHK1
反应种属:
Human
宿主来源:
Rabbit
实验应用:
ICC/IF, WB
同种型:
IgG
免疫原:
Carrier-protein conjugated synthetic peptide surrounding phospho Ser345 of human Chk1. The exact sequence is proprietary.
克隆性:
Monoclonal
克隆号:
HL122
纯化方式:
Affinity purified by Protein A.
偶联:
Unconjugated
产品浓度:
1 mg/ml (Please refer to the vial label for the specific concentration.)
保存温度:
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
运输温度:
4°C
产品形式:
Liquid
存储溶液:
PBS, no preservatives.
生产商:
GeneTex
功能与背景:
The protein encoded by this gene belongs to the Ser/Thr protein kinase family. It is required for checkpoint mediated cell cycle arrest in response to DNA damage or the presence of unreplicated DNA. This protein acts to integrate signals from ATM and ATR, two cell cycle proteins involved in DNA damage responses, that also associate with chromatin in meiotic prophase I. Phosphorylation of CDC25A protein phosphatase by this protein is required for cells to delay cell cycle progression in response to double-strand DNA breaks. Several alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Oct 2011]

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