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DEL-22379|22433-50 mg|CAS:181223-80-3
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DEL-22379|22433-50 mg|CAS:181223-80-3

22433-50 mg
DEL-22379
¥ 10639.6
¥ 10639.6
50 mg
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DEL-22379介绍:

产品名称:
DEL-22379
产品描述:
An inhibitor of ERK dimerization (IC50 = ~0.5 μM for disruption of EGF-induced co-immunoprecipitation of ERK); has no effect on ERK phosphorylation or kinase activity (IC50s = >10 μM); inhibits cell growth in a panel of melanoma and colorectal cancer cell lines (IC50s = 150-400 nM); inhibits ERK dimerization in liver extract and tumor tissue and inhibits tumor progression in an A375 mouse xenograft model at 15 mg/kg; reduces tumor growth in a BRAF mutant colorectal cancer PDX mouse model
保存温度:
-20
运输温度:
-20
预期分子量:
444.5
产品形式:
A crystalline solid
有效期:
1460
纯度:
≥98% (mixture of rotamers)
CAS号:
181223-80-3
分子式:
C26H28N4O3

本公司销售的所有产品仅供实验科研使用,不用于人体及临床诊断。

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