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VU0360172 (hydrochloride)|22074-10 mg|CAS:1309976-62-2
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VU0360172 (hydrochloride)|22074-10 mg|CAS:1309976-62-2

22074-10 mg
VU0360172 (hydrochloride)
¥ 2130.6
¥ 2130.6
10 mg
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VU0360172 (hydrochloride)介绍:

产品名称:
VU0360172 (hydrochloride)
产品描述:
A positive allosteric modulator of mGluR5 (Ki = 195 nM); selective for mGluR5 over mGluR1, mGluR3, and mGluR4 at 10 µM; prevents TNF-α and NO production by IFN-γ- or LPS-stimulated BV-2 and primary microglial cells at 20 and 50 µM; reduces expression of iNOS and increases expression of Ym1 and arginase 1 in LPS-stimulated BV-2 cells at 20 µM; reduces the size of cortical lesions, prevents hippocampal neurodegeneration, and improves sensorimotor deficits in the beam walk test in a mouse model of traumatic brain injury (TBI)
保存温度:
-20
运输温度:
-20
预期分子量:
294.34
产品形式:
A crystalline solid
有效期:
1460
纯度:
≥98%
CAS号:
1309976-62-2
分子式:
C18H15FN2O • HCl

本公司销售的所有产品仅供实验科研使用,不用于人体及临床诊断。

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