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JNJ-38877605|27650-10 mg|CAS:943540-75-8
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JNJ-38877605|27650-10 mg|CAS:943540-75-8

27650-10 mg
JNJ-38877605
¥ 2117.2
¥ 2117.2
943540-75-8
10 mg
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JNJ-38877605介绍：

产品名称:
JNJ-38877605
产品描述:
An ATP-competitive inhibitor of Met kinase (IC50 = 4 nM); at least 600-fold selective for Met in a panel of ~250 tyrosine and serine-threonine kinases; inhibits the growth of cancer cell lines with MET gene amplification (IC50s = 11-50 nM) but has no effect on the growth of control cells with normal MET gene copy number or no MET expression; sensitizes tumors to radiotherapy in U251 glioma and MDA-MB-231 breast cancer mouse xenograft models and increases apoptosis in irradiated tumors in the MDA-MB-231 mouse xenograft model at 50 mg/kgp; reduces tumor size by 6-fold and the number of blood vessels in tumors by 80% in an RU-P melanoma mouse xenograft model at 20 mg/kg
保存温度:
-20
运输温度:
-20
预期分子量:
377.350506
产品形式:
A crystalline solid
有效期:
1460
纯度:
≥98%
CAS号:
943540-75-8
分子式:
C19H13F2N7

本公司销售的所有产品仅供实验科研使用，不用于人体及临床诊断。

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