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INCB 3344|28433-5 mg|CAS:1262238-11-8

产品编号

28433-5 mg

英文名称

INCB 3344

标准价

~~¥ 5065.2~~

优惠价

¥ 5065.2

CAS号

1262238-11-8

规格

5 mg

有效期

品牌

萘析精选

标准值

见详情

数量

− +

库存

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INCB 3344介绍：

产品名称:

INCB 3344

产品描述:

An antagonist of CCR2 (IC50 = 10 nM); selective for CCR2 over a panel of G protein-coupled receptors, including CCR1 and CCR5, with IC50s values >1 µM; inhibits MCP-1-induced chemotaxis of WEHI-274 cells (IC50 = 10 nM); inhibits monocyte influx in a thioglycolate-induced mouse model of peritonitis at 60 and 100 mg/kg; decreases the expression of CCR2 mRNA in the ear and reduces ear swelling in a mouse model of delayed-type hypersensitivity reaction at 30, 50, and 100 mg/kg twice per day; prevents increases in or reduces macrophage levels in the spinal cord at 100 mg/kg per day beginning the day of immunization or seven days following immunization, respectively, in a mouse model of EAE

保存温度:

-20

运输温度:

-20

预期分子量:

577.592089

产品形式:

A solid

有效期:

1460

纯度:

≥95%

CAS号:

1262238-11-8

分子式:

C29H34F3N3O6

本公司销售的所有产品仅供实验科研使用，不用于人体及临床诊断。

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