跳至内容
当前位置: 首页 产品中心 分析试剂 生物试剂 TP-0903|28757-5 mg|CAS:1341200-45-0
TP-0903|28757-5 mg|CAS:1341200-45-0
图片仅供参考,具体产品以实物为准!

TP-0903|28757-5 mg|CAS:1341200-45-0

28757-5 mg
TP-0903
¥ 2251.2
¥ 2251.2
5 mg
萘析精选
见详情
− +
0
TP-0903介绍:

产品名称:
TP-0903
产品描述:
An inhibitor of Axl (IC50 = 27 nM ); exhibits greater than 50% inhibition of 11 kinases, including MER, TYRO3, JAK2, ALK, and Abl1, in a panel of 75 kinases at 200 nM, with IC50 values of 3 and 12.4 nM for Aurora A and B, respectively; decreases the phosphorylation of Akt and Axl in GAS6-stimulated, serum-starved PSN-1 pancreatic cancer cells (EC50s = 305 and 222 nM, respectively); decreases cell viability (IC50 = 6 nM) and induces cell cycle arrest at the G2/M phase in PSN-1 cells at 30 nM; reduces the viability of CRC cell lines (IC50s = 4.5-123 nM); exhibits 69 and 44% tumor growth inhibition in an HCT116 mouse xenograft model and a K-Ras-mutant CRC PDX mouse model, respectively, at 40 mg/kg
保存温度:
-20
运输温度:
-20
预期分子量:
516.05968
产品形式:
A crystalline solid
有效期:
1460
纯度:
≥98%
CAS号:
1341200-45-0
分子式:
C24H30ClN7O2S

本公司销售的所有产品仅供实验科研使用,不用于人体及临床诊断。

暂无标准解读内容
暂无常见问题内容