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Glumetinib|28952-10 mg|CAS:1642581-63-2
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Glumetinib|28952-10 mg|CAS:1642581-63-2

28952-10 mg
Glumetinib
¥ 4274.6
¥ 4274.6
10 mg
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Glumetinib介绍:

产品名称:
Glumetinib
别名:
SCC244
产品描述:
A potent c-Met inhibitor (IC50 = 0.42 nM); >2,400-fold selective for c-Met over a panel of 312 kinases; inhibits c-Met phosphorylation in and proliferation of MET-overexpressing EBC-1 lung and MKN45 gastric cancer cells from 0.001-1 μM; inhibits HGF-induced NCI H441 cell motility and invasion at 10 nM; reduces tumor volume in MKN45, SNU-5, and EBC-1 mouse xenograft models from 2.5-10 mg/kg; reduces tumor growth in MET amplification-containing NSCLC and HCC PDX mouse models
保存温度:
-20
运输温度:
-20
预期分子量:
459.48514
产品形式:
A crystalline solid
有效期:
1460
纯度:
≥98%
CAS号:
1642581-63-2
分子式:
C21H17N9O2S

本公司销售的所有产品仅供实验科研使用,不用于人体及临床诊断。

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