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AZD 8835|29166-25 mg|CAS:1620576-64-8
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AZD 8835|29166-25 mg|CAS:1620576-64-8

29166-25 mg
AZD 8835
¥ 6525.8
¥ 6525.8
25 mg
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AZD 8835介绍:

产品名称:
AZD 8835
产品描述:
An inhibitor of PI3Kα and PI3Kδ (IC50s = 6.2 and 5.7 nM, respectively); selective for PI3Kα and PI3Kδ over PI3Kβ and PI3Kγ (IC50s = 431 and 90 nM, respectively); inhibits Akt phosphorylation in PIK3CA constitutively active mutant BT474 cells and Jeko-1 B cells that express endogenous PI3Kδ (IC50s = 57 and 49 nM, respectively); reduces tumor growth and Akt phosphorylation in an SKOV3 mouse xenograft model at 25 mg/kg; increases the activity of CD8+ effector T cells and reduces tumor growth in a C26 mouse syngeneic tumor model
保存温度:
-20
运输温度:
-20
预期分子量:
469.5404
产品形式:
A crystalline solid
有效期:
1460
纯度:
≥98%
CAS号:
1620576-64-8
分子式:
C22H31N9O3

本公司销售的所有产品仅供实验科研使用,不用于人体及临床诊断。

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