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Zotarolimus|29246-1 mg|CAS:221877-54-9
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Zotarolimus|29246-1 mg|CAS:221877-54-9

29246-1 mg
Zotarolimus
¥ 482.4
¥ 482.4
1 mg
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Zotarolimus介绍:

产品名称:
Zotarolimus
别名:
A-179578|ABT-578
产品描述:
A macrocyclic lactone immunosuppressant; binds to FKBP12 (IC50 = 2.57 nM); inhibits proliferation of human PBMCs, rat splenocytes, and human coronary artery smooth muscle cells (IC50s = 7, 1,337, and 0.8 nM, respectively); has immunosuppressive activity in a one-way mixed lymphocyte reaction using human or rat lymphocytes (IC50s = 1.2 and 1,465 nM, respectively); reduces symptom severity in a rat model of EAE (ED50 = 1.17 mg/kg per day); delays cardiac allograft rejection in rats (ED50 = 3.71 mg/kg per day); inhibits neointimal formation and reduces stenosis in pig coronary arteries when applied at 10 µg/mm to stainless steel balloon expandable stents with phosphorylcholine in a model of restenosis
保存温度:
-20
运输温度:
-20
预期分子量:
966.21016
产品形式:
A solid
有效期:
1460
纯度:
≥95% (mixture of isomers)
CAS号:
221877-54-9
分子式:
C52H79N5O12

本公司销售的所有产品仅供实验科研使用,不用于人体及临床诊断。

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