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SAR20347|29248-25 mg|CAS:1450881-55-6
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SAR20347|29248-25 mg|CAS:1450881-55-6

29248-25 mg
SAR20347
¥ 7517.4
¥ 7517.4
25 mg
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SAR20347介绍:

产品名称:
SAR20347
产品描述:
A JAK family kinase inhibitor (IC50s = 0.6, 23, 26, and 41 nM, for TYK2 and JAK1-3, respectively, in cell-free assays); inhibits IL-12-induced TYK2-dependent phosphorylation of STAT4 in NK-92 cells (IC50 = 126 nM) and IL-6-induced JAK1-dependent phosphorylated STAT3 signaling in TF-1 cells (IC50 = 345 nM); inhibits IL-12-induced INF-γ production and reporter gene activity in PBMCs at 5 μM; inhibits the production of serum IFN-γ in mice at 60 mg/kg; reduces keratinocyte activation and skin levels of IL-12, IL-23, IL-6, IL-22 and IFN-γ in a mouse model of imiquimod-induced psoriasis
保存温度:
-20
运输温度:
-20
预期分子量:
444.843283
产品形式:
A solid
有效期:
1460
纯度:
≥98%
CAS号:
1450881-55-6
分子式:
C21H18ClFN4O4

本公司销售的所有产品仅供实验科研使用,不用于人体及临床诊断。

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