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DS-437|29476-5 mg|CAS:1674364-87-4

产品编号

29476-5 mg

英文名称

DS-437

标准价

~~¥ 1554.4~~

优惠价

¥ 1554.4

CAS号

1674364-87-4

规格

5 mg

有效期

品牌

萘析精选

标准值

见详情

数量

− +

库存

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DS-437介绍：

产品名称:

DS-437

产品描述:

A dual inhibitor of PRMT5 and PRMT7 (IC50s = 5.9 and 6 μM, respectively); selective for PRMT5 and PRMT7 over a panel of 29 additional protein, DNA, and RNA methyltransferases at 50 μM, but also inhibits DNMT3A and DNMT3B (IC50s = 52 and 62 μM, respectively); inhibits symmetrical arginine dimethylation of FOXP3 in HEK293T cells at 2.5 and 10 μM; inhibits the ability of Tregs to suppress Teff proliferation in vitro in human and murine Treg suppression assays; reduces tumor growth in a CT26Her2 murine colon cancer model when administered at 10 mg/kg five times per week in combination with the anti-p185erbB2/neu antibody 4D5

保存温度:

-20

运输温度:

-20

预期分子量:

397.4539

产品形式:

A solid

有效期:

1460

纯度:

≥98%

CAS号:

1674364-87-4

分子式:

C15H23N7O4S

本公司销售的所有产品仅供实验科研使用，不用于人体及临床诊断。

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