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YM-976|29529-25 mg|CAS:191219-80-4

产品编号

29529-25 mg

英文名称

YM-976|29529-25 mg|CAS:191219-80-4

标准价

~~¥ 5721.8~~

优惠价

¥ 5721.8

CAS号

191219-80-4

规格

25 mg

有效期

品牌

萘析精选

标准值

见详情

数量

− +

库存

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YM-976介绍：

产品名称:

YM-976

产品描述:

A PDE4 inhibitor (IC50 = 2.2 nM for the human peripheral leukocyte enzyme); selective for PDE4 over PDE1, -2, -3, and -5 (IC50s = >3 µM for all); inhibits LPS-induced TNF-α production in human PBMCs; inhibits carrageenan-induced pleural cavity cell infiltration in a rat model of pleurisy (ED30 = 9.1 mg/kg); inhibits antigen-induced lung eosinophil infiltration in rats, mice, and ferrets (ED50s = 1.7, 5.8, and 1.2 mg/kg, respectively); does not induce emesis in ferrets at doses up to 10 mg/kg; reduces ovalbumin-induced bronchoconstriction, as well as airway plasma leakage, eosinophil infiltration, and hyperreactivity in a guinea pig model of asthma (ED50s = 7.3, 5.7, 1, and 0.52 mg/kg, respectively); reduces citric acid-induced cough in guinea pigs

保存温度:

-20

运输温度:

-20

预期分子量:

313.78126

产品形式:

A solid

有效期:

1460

纯度:

≥98%

CAS号:

191219-80-4

分子式:

C17H16ClN3O

本公司销售的所有产品仅供实验科研使用，不用于人体及临床诊断。

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