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TAK-779|26744-5 mg|CAS:229005-80-5
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TAK-779|26744-5 mg|CAS:229005-80-5

26744-5 mg
TAK-779
¥ 1902.8
¥ 1902.8
5 mg
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TAK-779介绍:

产品名称:
TAK-779
产品描述:
An antagonist of CCR5, CCR2b, and CXCR3; inhibits CCR5 and CXCR3 (IC50s = 236 and 369 nM, respectively) and CCR5 and CCR2b (IC50s = 1.4 and 27 nM, respectively); inhibits the replication of clinical isolates of R5, but not X4, HIV-1 in human PBMCs (EC50s = 1.6-3.5 and >20,000 nM, respectively); inhibits ovalbumin-induced increases in CCR5, CXCR3, IFN-γ, and TNF-α expression in mouse lung, as well as the number of total cells, lymphocytes, and eosinophils in BALF, in a mouse model of asthma at 250 mg per animal per day; increases intestinal allograft survival in a rat model of small intestine transplantation at 10 mg/kg per day
保存温度:
-20
运输温度:
-20
预期分子量:
495.67504
产品形式:
A crystalline solid
有效期:
1460
纯度:
≥98%
CAS号:
229005-80-5
分子式:
C33H39N2O2 • Cl

本公司销售的所有产品仅供实验科研使用,不用于人体及临床诊断。

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