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PD 166285|26804-25 mg|CAS:185039-89-8
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PD 166285|26804-25 mg|CAS:185039-89-8

26804-25 mg
PD 166285
¥ 7155.6
¥ 7155.6
185039-89-8
25 mg
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PD 166285介绍：

产品名称:
PD 166285
产品描述:
A tyrosine kinase inhibitor; inhibits Src, FGFR1, EGFR, and PDGFRβ (IC50s = 8.4, 39.3, 87.5, and 98.3 nM, respectively), as well as WEE1 (IC50 = 24 nM); inhibits PDGF- or EGF-induced receptor autophosphorylation in VSMCs and A431 cells, respectively, and bFGF-induced tyrosine phosphorylation in Sf9 cells (IC50s = 6.5, 1,600, and 97.3 nM, respectively); inhibits chemotaxis and growth of, as well as adhesion to vitronectin by, VSMCs (IC50s = 80-120 nM); inhibits radiation-induced cell cycle arrest at the G2/M phase and enhances radiation-induced cell death in HT-29 cells; inhibits angiogenesis and induces tumor regression in a 16c murine mammary carcinoma model when administered in combination with PDT at 1, 5, and 10 mg/kg
保存温度:
-20
运输温度:
-20
预期分子量:
512.43048
产品形式:
A solid
有效期:
1460
纯度:
≥98%
CAS号:
185039-89-8
分子式:
C26H27Cl2N5O2

本公司销售的所有产品仅供实验科研使用，不用于人体及临床诊断。

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