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AC480|29657-25 mg|CAS:714971-09-2

产品编号

29657-25 mg

英文名称

AC480

标准价

~~¥ 7517.4~~

优惠价

¥ 7517.4

CAS号

714971-09-2

规格

25 mg

有效期

品牌

萘析精选

标准值

见详情

数量

− +

库存

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AC480介绍：

产品名称:

AC480

别名:

BMS-599626

产品描述:

A dual inhibitor of EGFR and HER2 (IC50s = 22 and 32 nM, respectively); selective for EGFR and HER2 over HER4 (IC50 = 190 nM) and a panel of 21 additional kinases (IC50s = >2,500 nM for all); inhibits proliferation in a panel of EGFR and/or HER2 signaling-dependent cancer cells (IC50s = 0.24-0.94 μM); reduces tumor growth in a Sal2 murine salivary gland tumor model, as well as GEO colon and KPL4 breast cancer mouse xenograft models in a dose-dependent manner; reduces tumor cell motility, intravasation, and EGF-induced invasion in an MTLn3E metastatic mammary adenocarcinoma mouse xenograft model at 100 mg/kg

保存温度:

-20

运输温度:

-20

预期分子量:

530.553803

产品形式:

A crystalline solid

有效期:

1460

纯度:

≥98%

CAS号:

714971-09-2

分子式:

C27H27FN8O3

本公司销售的所有产品仅供实验科研使用，不用于人体及临床诊断。

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