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SB-328437|29677-1 mg|CAS:247580-43-4
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SB-328437|29677-1 mg|CAS:247580-43-4

29677-1 mg
SB-328437
¥ 509.2
¥ 509.2
1 mg
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SB-328437介绍:

产品名称:
SB-328437
产品描述:
A CCR3 antagonist (IC50 = 4.5 nM in a radioligand binding assay); selective for CCR3 over CXCR1, CXCR2, CCR7, C3aR, and C5aR (IC50s = >27, >27, >33, >10, and >10 µM, respectively); inhibits calcium mobilization induced by C-C motif ligand 11 CCL11, CCL24, and CCL13 in RBL-2H3-CCR3 cells and eosinophils from 3.3-1,000 nM; reduces pulmonary Ccr3 mRNA expression, the number of eosinophils and monocytes in BALF, and pulmonary IL-4 and TNF-α levels in a mouse model of asthma
保存温度:
-20
运输温度:
-20
预期分子量:
378.3781
产品形式:
A crystalline solid
有效期:
1460
纯度:
≥98%
CAS号:
247580-43-4
分子式:
C21H18N2O5

本公司销售的所有产品仅供实验科研使用,不用于人体及临床诊断。

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