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NNC-711 (hydrochloride)|29687-1 mg|CAS:145645-62-1
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NNC-711 (hydrochloride)|29687-1 mg|CAS:145645-62-1

29687-1 mg
NNC-711 (hydrochloride)
¥ 482.4
¥ 482.4
145645-62-1
1 mg
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NNC-711 (hydrochloride)介绍：

产品名称:
NNC-711 (hydrochloride)
别名:
NNC 05-711|NO-711
产品描述:
A GAT-1 inhibitor (IC50 = 0.04 µM for the human transporter); selective for GAT-1 over human GAT-3 and BGT-3 (IC50s = 1,700 and 622 µM, respectively), rat GAT-2 (IC50 = 171 µM), and a panel of 21 receptors and ion channels (IC50s = >50 µM for all) in radioligand binding assays; inhibits GABA uptake in rat synaptosome preparations, neurons, and glia (IC50s = 47, 1,238, and 636 nM, respectively); inhibits PTZ- or DMCM-induced clonic seizures in mice (ED50s = 1.2 and 3 mg/kg, respectively), as well as audiogenic tonic seizures in mice (ED50 = 0.23 mg/kg) and PTZ-induced tonic seizures in rats (ED50 = 1.7 mg/kg); intrathecal administration decreases mechanical allodynia and thermal hyperalgesia in a rat model of CCI-induced neuropathic pain at 100 or 200 µg/animal
保存温度:
-20
运输温度:
-20
预期分子量:
350.41106
产品形式:
A crystalline solid
有效期:
1460
纯度:
≥98%
CAS号:
145645-62-1
分子式:
C21H22N2O3 • HCl

本公司销售的所有产品仅供实验科研使用，不用于人体及临床诊断。

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