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Parsaclisib|29784-5 mg|CAS:1426698-88-5
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Parsaclisib|29784-5 mg|CAS:1426698-88-5

29784-5 mg
Parsaclisib
¥ 4984.8
¥ 4984.8
1426698-88-5
5 mg
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Parsaclisib介绍：

产品名称:
Parsaclisib
别名:
INCB 050465
产品描述:
A PI3Kδ inhibitor (IC50 = 1 nM); selective for PI3Kδ over PI3Kα, PI3Kβ, and PI3Kγ (IC50s = >10,000 nM for all), as well as a panel of 192 additional kinases and a panel of 70 ion channels and transporters at 1 µM; inhibits primary human B cell proliferation (IC50 = 0.2 nM) and memory T cell cytokine production (IC50s = 0.2-1.5 nM); inhibits the differentiation of naïve isolated human T cells into Th1, Th2, or Th17 T helper cells; inhibits the proliferation of JeKo-1, Mino, Rec-1, and JVM-2 lymphoma cells (IC50s = 50s = 2-8 nM); reduces intratumoral phosphorylation of Akt and tumor growth in a Pfeiffer mouse xenograft model from 0.1-10 mg/kg; reduces proteinuria, lymphadenopathy, and the severity of skin lesions in an MRL/MpJ-Fas lpr mouse model of spontaneous SLE at 3 mg/kg; reduces salivary levels of TNFSF13B and plasma levels of anti-SSA and anti-SSB autoantibodies in a NOD.ShiLtJ mouse model of Sjögren’s syndrome
保存温度:
-20
运输温度:
-20
预期分子量:
432.879023
产品形式:
A solid
有效期:
1460
纯度:
≥95%
CAS号:
1426698-88-5
分子式:
C20H22ClFN6O2

本公司销售的所有产品仅供实验科研使用，不用于人体及临床诊断。

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