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CAY10746|29814-500 µg|CAS:2247240-76-0
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CAY10746|29814-500 µg|CAS:2247240-76-0

29814-500 µg
CAY10746
¥ 2264.6
¥ 2264.6
2247240-76-0
500 µg
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CAY10746介绍：

产品名称:
CAY10746
产品描述:
A ROCK1 and ROCK2 inhibitor (IC50s = 14 and 3 nM, respectively); selective for ROCK1 and ROCK2 over PKA (IC50 = >10,000 nM) and over 387 recombinant human protein kinases in a panel of 394 kinases (IC50s = >10,000 nM for all) but does inhibit LIMK2, Aurora A, Aurora B, PKG1α, and PKG1β (IC50s = 46, 1,072, 1,239, 517, and 660 nM, respectively); inhibits phosphorylation of MYPT1 in SH-SY5Y cells at 0.1-10 µM; inhibits HUVEC migration at 1 µM; protects isolated mouse retinal neurons from apoptosis and oxidative stress induced by high glucose in an in vitro model of diabetic retinopathy; promotes high glucose-induced vessel regression in mouse retinal explants
保存温度:
-20
运输温度:
-20
预期分子量:
457.47804
产品形式:
A crystalline solid
有效期:
1460
纯度:
≥95%
CAS号:
2247240-76-0
分子式:
C26H23N3O5

本公司销售的所有产品仅供实验科研使用，不用于人体及临床诊断。

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