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CGP 7930|29429-5 mg|CAS:57717-80-3
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CGP 7930|29429-5 mg|CAS:57717-80-3

29429-5 mg
CGP 7930
¥ 1916.2
¥ 1916.2
57717-80-3
5 mg
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CGP 7930介绍：

产品名称:
CGP 7930
产品描述:
A positive allosteric modulator of GABAB receptors; enhances GABA binding with a maximal effect of 143% compared to a GABA-only control in CHO cells membranes expressing the GABAB(1b/2) receptor and enhances GABA binding to rat cortical membranes at 30 µM; selective for GABA binding to heterodimeric GABAB(1b/2) over monomeric GABAB(1b) receptors; potentiates the efficacy of baclofen in decreasing the spontaneous firing rate of dopaminergic neurons in the rat VTA in vitro (EC50 = 0.27 µM); also potentiates the sedative-reducing effects induced by baclofen or GHB in rats at 10-170 mg/kg; suppresses the acquisition of alcohol drinking behavior in alcohol-naïve Sardinian alcohol-preferring rats over a five-day period at 25-100 mg/kg and transiently reduces the maintenance of alcohol drinking behavior in alcohol-experienced rats at a dose of 100 mg/kg
保存温度:
-20
运输温度:
-20
预期分子量:
292.45618
产品形式:
A crystalline solid
有效期:
1460
纯度:
≥98%
CAS号:
57717-80-3
分子式:
C19H32O2

本公司销售的所有产品仅供实验科研使用，不用于人体及临床诊断。

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