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JTE-907|10009857-1 mg|CAS:282089-49-0
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JTE-907|10009857-1 mg|CAS:282089-49-0

10009857-1 mg
JTE-907
¥ 924.6
¥ 924.6
1 mg
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JTE-907介绍:

产品名称:
JTE-907
产品描述:
A CB2 receptor inverse agonist; selective for CB2 over CB1 receptors (Kis = 35.9 and 2,370 nM, respectively, for the human receptors); increases forskolin-induced cAMP production in CHO cells expressing human or mouse CB2 receptors; promotes the differentiation of isolated mouse splenic CD4+ T cells into Tregs at 100 nM; decreases disease severity in a mouse model of DNBS-induced IBD; inhibits spontaneous scratching in a mouse model of chronic dermatitis at 1 and 10 mg/kg; reduces carrageenan-induced paw edema in mice (ED50 = 0.05 mg/kg); bilateral injection into the anterior bed nucleus of the stria terminalis decreases the percentage of time spent in the open arms of the elevated plus maze in mice, indicating anxiety-like behavior, at 25 pmol/animal
保存温度:
-20
运输温度:
-20
预期分子量:
438.5
产品形式:
A crystalline solid
有效期:
1460
纯度:
≥98%
CAS号:
282089-49-0
分子式:
C24H26N2O6

本公司销售的所有产品仅供实验科研使用,不用于人体及临床诊断。

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