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Sodium Butyrate|13121-50 g|CAS:156-54-7
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Sodium Butyrate|13121-50 g|CAS:156-54-7

13121-50 g
Sodium Butyrate
¥ 482.4
¥ 482.4
50 g
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Sodium Butyrate介绍:

产品名称:
Sodium Butyrate
别名:
Butyric Acid|FA 4:0
产品描述:
A short-chain fatty acid; produced predominately by bacterial fermentation of dietary fiber in the colon but has also been identified in mammalian milk; an HDAC inhibitor (IC50 = 90 µM in a cell-free assay); induces differentiation, cell cycle arrest at the G0 phase, and apoptosis, as well as inhibits proliferation, in a variety of cancer cells from 0.6-100 mM; decreases the expression of IFN-γ-related signaling genes and metastatic genes in H460 human lung cancer cells at 2 mM; reduces tumor growth in a CaSki mouse xenograft model at 200 and 800 mg/kg per day; reduces increases in colonic TNFa and Il6 expression and decreases colonic goblet cell depletion, tissue damage, muscle thickening, and cellular infiltration in a wild-type, but not Hcar2-/-, mouse model of TNBS-induced colitis
保存温度:
22
运输温度:
22
预期分子量:
110.1
产品形式:
A crystalline solid
有效期:
1460
纯度:
≥95%
来源:
Synthetic
CAS号:
156-54-7
分子式:
C4H7O2 • Na

本公司销售的所有产品仅供实验科研使用,不用于人体及临床诊断。

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