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Voclosporin|39719-10 mg|CAS:515814-01-4
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Voclosporin|39719-10 mg|CAS:515814-01-4

39719-10 mg
Voclosporin
¥ 14271.0
¥ 14271.0
515814-01-4
10 mg
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Voclosporin介绍：

产品名称:
Voclosporin
别名:
(E)-ISA247|ISATX247|LX211|R-15424|trans-ISA 247
产品描述:
An immunosuppressant; binds to cyclophilin A (Kd = 15 nM); inhibits calcineurin activity in isolated human whole blood (IC50 = 120 ng/ml); reduces the proliferation of, and production of IL-2, IFN-γ, and TNF-α in, isolated cynomolgus monkey lymphocytes (EC50s = 202.79, 135.32, 177.11, and 138.56 ng/ml, respectively); decreases disease severity in a rat model of IRBP-induced experimental autoimmune uveoretinitis from 2.5-40 mg/kg; increases graft survival in a rat model of heterotopic heart transplantation at 1.75 mg/kg; unlike cyclosporin A, it does not increase serum creatinine levels in rabbits; inhibits the replication of SARS-CoV-2 in infected Calu-3 cells
保存温度:
-20
运输温度:
-20
预期分子量:
1214.62238
产品形式:
A solid
有效期:
1460
纯度:
≥98%
CAS号:
515814-01-4
分子式:
C63H111N11O12

本公司销售的所有产品仅供实验科研使用，不用于人体及临床诊断。

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