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P276-00 (hydrochloride)|39845-5 mg|CAS:920113-03-7
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P276-00 (hydrochloride)|39845-5 mg|CAS:920113-03-7

39845-5 mg
P276-00 (hydrochloride)
¥ 3939.6
¥ 3939.6
920113-03-7
5 mg
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P276-00 (hydrochloride)介绍：

产品名称:
P276-00 (hydrochloride)
别名:
Riviciclib
产品描述:
A Cdk9, Cdk4, and Cdk1 inhibitor (IC50s = 0.020, 0.063, and 0.079 µM, respectively); selective for these CDKs over Cdk2/cyclin E, Cdk2/cyclin A, Cdk6, and Cdk7 (IC50s = 2.54, 0.224, 0.396, and 2.87 µM, respectively), as well as a panel of eight other kinases; induces apoptosis in HL-60 cells at 1 µM; induces cell cycle arrest at the G1 phase in synchronized H460 cells at 1.5 and 5 µM; reduces tumor volume in a H460 mouse xenograft model at 50 mg/kg once per day; inhibits reactivation of latent HIV-1 induced by prostratin, panobinostat, or JQ-1 in 24ST1NLESG cells (IC50s = 0.1, 0.07, and 0.075 µM, respectively)
保存温度:
-20
运输温度:
-20
预期分子量:
401.83994
产品形式:
A solid
有效期:
1460
纯度:
≥98%
CAS号:
920113-03-7
分子式:
C21H20ClNO5 • HCl

本公司销售的所有产品仅供实验科研使用，不用于人体及临床诊断。

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