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Naveni PD1/PD-L1 BOND RX HRP|41651|30 Slides
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Naveni PD1/PD-L1 BOND RX HRP|41651|30 Slides

41651
Naveni PD1/PD-L1 BOND RX HRP
¥ 53827.8
¥ 53827.8
30 Slides
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Naveni PD1/PD-L1 BOND RX HRP介绍:

产品名称:
Naveni PD1/PD-L1 BOND RX HRP
产品描述:
The Naveni® PD1/PD-L1 BOND RX HRP is an in situ proximity ligation assay kit for the detection of the interaction of PD1 and PD-L1 using BOND RX/RXm Fully Automated Research Stainer. The kit has been validated on FFPE human tissue samples. The kit is based on the Naveni® in situ proximity ligation technology with an automated workfflow. It uses two Navenibodies linked to proprietary oligo arms. The primary antibodies included in the kit bind to PD1 and PD-L1 proteins, while Navenbodies then bind to their respective primary antibodies. When Navenbodies are in close proximity, a strong and distinct signal is generated, offering a specific and sensitive detection method for the interaction between PD1 and PD-L1. Read more about Naveni technology. Included in the kit: • Navenibody targeting human PD1 protein based on clone EH33 CST • Navenibody targeting human PD-L1 protein based on clone SP142 Abcam RabMAb® • Buffers for blocking and dilutions, and all detection reagents for the PD1/PD-L1 interaction signal • Reagents sufficient for 30 FFPE tissue slides, including dead volumes Not included in the kit: • Leica Biosystems for BOND RX/RXm with standard accessories. • Mounting medium Find better prognostic biomarkers PD1/PD-L1 signaling has with immune checkpoint inhibitors proven to be significant in cancer progression and treatment. Despite the recent success of immune checkpoint inhibitors, many patients do not benefit from these therapies, and predictive biomarkers improving patient stratification are needed. PD-L1 IHC is commonly used as a biomarker, but the correlation between PD-L1 expression levels and PD1/PD-L1 interaction is not alwyas linear. Naveni® PPI Proteins perform a wide range of functions and are the cloest way to understand biology. Proteins are also key targets in both health and disease. When proteins carry out their function, they interact with other proteins or molecules. To understand biological pathways and mode of action, we need to get a deeper insight into protein functions and how the protein interacts. Detecting the interactions has until now been either complicated, unspecific, or insensitive. The Naveni® in situ proximity ligation technology enables visualization of protein-protein interaction using one primary antibody for each target protein, without the need to disrupt the tissue microenvironment.
实验应用:
ICC and IHC
保存温度:
-20
运输温度:
-20
有效期:
180

本公司销售的所有产品仅供实验科研使用,不用于人体及临床诊断。

Naveni PD1/PD-L1 BOND RX HRP|41651|30 Slides 国标解读

Naveni PD1/PD-L1 BOND RX HRP|41651|30 Slides 为本库在售产品。经核查,本库标准库中未收录其专属产品质量国家标准,对其质量与安全性评价可依据化学试剂通用试验方法标准与安全类标准执行

标准号标准名称适用说明
GB/T 619-1988化学试剂 采样及验收规则试剂取样与验收通用程序
GB/T 6682-2008分析实验室用水规格和试验方法试验用水要求
GB/T 9724-2007化学试剂 pH值测定通则酸碱度表征
GB/T 9735-2008化学试剂 重金属测定通用方法重金属杂质控制
GB/T 9736-2008化学试剂 酸度和碱度测定通用方法酸度/碱度
GB/T 9738-2008化学试剂 水不溶物测定通用方法水不溶物
GB/T 9739-2006化学试剂 铁测定通用方法铁杂质
GB/T 9741-2008化学试剂 灼烧残渣测定通用方法灼烧残渣
GB/T 9737-2008化学试剂 易炭化物质测定通则易炭化物质
GB 15346-2012化学试剂 包装及标志包装与标识
GB 13690-2009化学品分类和危险性公示 通则危险性分类
GB/T 16483-2008化学品安全技术说明书 内容和项目顺序安全信息(SDS)
GB 15258-2009化学品安全标签编写规定安全标签
GB 30000.18-2013化学品分类和标签规范 第18部分:急性毒性急性毒性标签

说明:本库内暂无该产品的专属产品质量国家标准,以上为化学试剂通用试验方法标准与安全类标准,实际验收应以生产企业标准或合同约定为准

以上标准解读仅供参考,请以相应标准的原文为准!

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