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DPTIP (hydrochloride)|41681-25 mg|CAS:2361799-64-4
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DPTIP (hydrochloride)|41681-25 mg|CAS:2361799-64-4

41681-25 mg
DPTIP (hydrochloride)
¥ 5708.4
¥ 5708.4
25 mg
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DPTIP (hydrochloride)介绍:

产品名称:
DPTIP (hydrochloride)
产品描述:
An nSMase2 inhibitor (IC50 = 30 nM); selective for nSMase2 over ALP and acid sphingomyelinase (IC50s = >100 µM for both); reduces viral yield in Vero and HeLa cells infected with West Nile virus (EC50s = 0.26 and 2.81 µM, respectively) or Zika virus (EC50s = 1.56 and 1.84 µM, respectively); prevents serum deprivation-induced astrocyte activation in primary rat astrocytes at 10 µM; reduces IL-1β-induced extracellular vesicle release from astrocytes, decreases neutrophil infiltration to the brain, and reduces hepatic levels of Ccl2, Tnf-α, Il-6, and Il-1β in a GFAP-GFP mouse model of inflammation-induced brain injury at 10 mg/kg
保存温度:
-20
运输温度:
-20
预期分子量:
378.4453
产品形式:
A solid
有效期:
1460
纯度:
≥95%
CAS号:
2361799-64-4
分子式:
C21H18N2O3S • HCl

本公司销售的所有产品仅供实验科研使用,不用于人体及临床诊断。

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