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CD11b antibody [MEM-170] (Azide Free)|GTX79994|100μg
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CD11b antibody [MEM-170] (Azide Free)|GTX79994|100μg

GTX79994
CD11b antibody [MEM-170] (Azide Free)
¥ 4700.0
¥ 4700.0
100μg
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CD11b antibody [MEM-170] (Azide Free)介绍:

产品名称:
CD11b antibody [MEM-170] (Azide Free)
别名:
CD11B , CR3A , ITGAM , MAC1 , MAC1A , MO1A , SLEB6 , integrin subunit alpha M , CD11b , Mac-1 , Macrophage 1 antigen
反应种属:
Human
宿主来源:
Mouse
实验应用:
FCM, Functional Assay
靶标/特异性:
This antibody recognizes CD11b antigen (Mac-1alpha), a 165-170 kDa transmembrane protein type 1 mainly expressed on monocytes, granulocytes and NK-cells. The antibody blocks (not completely) Mac-1-mediated neutrophil binding to fibrinogen.
同种型:
IgG1
免疫原:
Human granulocytes
克隆性:
Monoclonal
克隆号:
MEM-170
纯化方式:
Protein A purified
偶联:
Unconjugated
产品浓度:
1 mg/ml (Please refer to the vial label for the specific concentration.)
保存温度:
Store as concentrated solution. Centrifuge briefly prior to opening vial. Store at 4ºC. DO NOT FREEZE.
运输温度:
4°C
产品形式:
Liquid
存储溶液:
PBS, no preservatives.
生产商:
GeneTex
功能与背景:
This gene encodes the integrin alpha M chain. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. This I-domain containing alpha integrin combines with the beta 2 chain (ITGB2) to form a leukocyte-specific integrin referred to as macrophage receptor 1 ('Mac-1'), or inactivated-C3b (iC3b) receptor 3 ('CR3'). The alpha M beta 2 integrin is important in the adherence of neutrophils and monocytes to stimulated endothelium, and also in the phagocytosis of complement coated particles. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2009]

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