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Apolipoprotein B blocking peptide|GTX88654-PEP|100μg
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Apolipoprotein B blocking peptide|GTX88654-PEP|100μg

GTX88654-PEP
Apolipoprotein B blocking peptide
¥ 3200.0
¥ 3200.0
100μg
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Apolipoprotein B blocking peptide介绍:

产品名称:
Apolipoprotein B blocking peptide
别名:
Apolipoprotein B , Fldb , Ldlcq4 , Apob-100 , Apob-48 , Apob
靶标/特异性:
The peptide was used in the production of GTX88654.
克隆号:
产品浓度:
保存温度:
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
运输温度:
4°C
产品形式:
Lyophilized powder
存储溶液:
Reconstitute with 200μl distilled water to obtain a 0.5mg/ml peptide solution. Lyophilized from 5% (v/v) acetonitrile/H₂O, no preservatives.
生产商:
GeneTex
功能与背景:
This gene product is the main apolipoprotein of chylomicrons and low density lipoproteins. It occurs in plasma as two main isoforms, apoB-48 and apoB-100: the former is synthesized exclusively in the gut and the latter in the liver. The intestinal and the hepatic forms of apoB are encoded by a single gene from a single, very long mRNA. The two isoforms share a common N-terminal sequence. The shorter apoB-48 protein is produced after RNA editing of the apoB-100 transcript at residue 2180 (CAA->UAA), resulting in the creation of a stop codon, and early translation termination. Mutations in this gene or its regulatory region cause hypobetalipoproteinemia, normotriglyceridemic hypobetalipoproteinemia, and hypercholesterolemia due to ligand-defective apoB, diseases affecting plasma cholesterol and apoB levels. [provided by RefSeq, Jul 2008]

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