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CYP3A4 antibody, Internal|GTX89375|100μg
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CYP3A4 antibody, Internal|GTX89375|100μg

GTX89375
CYP3A4 antibody, Internal
¥ 5600.0
¥ 5600.0
100μg
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CYP3A4 antibody, Internal介绍：

产品名称:
CYP3A4 antibody, Internal
别名:
cytochrome P450 family 3 subfamily A member 4 , CP33 , CP34 , CYP3A , CYP3A3 , CYPIIIA3 , CYPIIIA4 , HLP , NF-25 , P450C3 , P450PCN1
反应种属:
Human
宿主来源:
Goat
实验应用:
FCM, ICC/IF
靶标/特异性:
This antibody is expected to recognise both reported isoforms (NP_059488.2; NP_001189784.1) and it is not expected to cross-react with 3A5, 3A7 ot 3A43.
同种型:
IgG
免疫原:
Peptide with sequence C-KESRLEDTQKHR, from the internal region of the protein sequence according to NP_059488.2; NP_001189784.1.
克隆性:
Polyclonal
克隆号:
纯化方式:
Purified by ammonium sulphate precipitation followed by antigen affinity chromatography
偶联:
Unconjugated
产品浓度:
0.50 mg/ml (Please refer to the vial label for the specific concentration.)
保存温度:
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
运输温度:
4°C
产品形式:
Liquid
存储溶液:
TBS, 0.5% BSA, 0.02% Sodium azide.
生产商:
GeneTex
功能与背景:
This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases that catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum and its expression is induced by glucocorticoids and some pharmacological agents. This enzyme is involved in the metabolism of approximately half the drugs in use today, including acetaminophen, codeine, cyclosporin A, diazepam and erythromycin. The enzyme also metabolizes some steroids and carcinogens. This gene is part of a cluster of cytochrome P450 genes on chromosome 7q21.1. Previously another CYP3A gene, CYP3A3, was thought to exist; however, it is now thought that this sequence represents a transcript variant of CYP3A4. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Feb 2011]

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